In order to study the influence of different process parameters on the bending angle during repeated laser scanning of Q235 medium-thick plates, a finite element model of temperature field transient distribution and thermoplastic material deformation during laser scanning was constructed by ABAQUS. The reliability of the finite element model was verified through experiments. A numerical simulation analysis was conducted to investigate the variation in the bending angle of the medium-thick plates during repeated laser scanning, and a mathematical model for predicting the bending angle was derived. The results show that under the condition that the line energy density range of 18 to 36 (J·mm-1) is maintained for laser bending, the bending angle increases as the plate thickness decreases, increases with the increase in laser power, increases linearly with the increase in the number of repeated scanning times, decreases with the increase in scanning speed, and first increases and then decreases with the increase in laser spot diameter. Selecting a laser spot diameter of 12 mm for scanning can improve the bending efficiency.