融合多尺度特征的脑肿瘤分割算法
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西南石油大学

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国家高技术研究发展计划(863计划)


Brain tumor segmentation algorithm based on multi-scale features
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Southwest Petroleum University

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The National High Technology Research and Development Program of China (863 Program)

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    摘要:

    脑肿瘤核磁共振图像分割是脑肿瘤诊断和治疗的重要环节,针对U-Net网络结构对图像特征感受野大小有所限制、上下文信息存在鸿沟导致的分割准确率较低的问题,本文提出了一种融合多尺度特征的脑肿瘤核磁共振图像分割算法。首先,设计了一种多尺度聚合模块(multiscale aggregation module, MAM)来替换原始U-Net网络中的常规卷积层,增加网络的深度以及宽度,来捕获特征图的边界细节信息。其次,在编码路径与解码路径中引入一个上下文空洞空间金字塔模块(context atrous spatial pyramid, CASP),扩大网络的感受野,增强网络获得多尺度特征的能力。最后,在编解码路径的交界处设计了一个多层次聚合注意力模块(multi-level aggregation attention, MAA),使网络模型关注图像分割区域有效特征,排除背景噪声。将改进算法在癌症基因组图谱(脑肿瘤数据)数据库上进行实验验证,其结果表明所提算法的平均交并比、Dice系数、敏感性、特异性、准确率等指标分别为:91.39%、92.81%、89.14%、99.95%、95.78%。

    Abstract:

    Brain tumor MRI image segmentation is an important part of brain tumor diagnosis and treatment, aiming at the problem that the U-Net network structure has limited the size of the image feature receptive field and the gap in the context information caused by the low segmentation accuracy, this paper proposes a brain tumor MRI image segmentation algorithm that integrates multi-scale features. Firstly, a multiscale aggregation module (MAM) is designed to replace the conventional convolutional layer in the original U-Net network, increase the depth and width of the network, and capture the boundary details of the feature map. Secondly, a context atrous spatial pyramid (CASP) module is introduced in the encoding path and decoding path to expand the receptive field of the network and enhance the ability of the network to obtain multi-scale features. Finally, a multi-level aggregation attention module (MAA) is designed at the junction of the codec path, so that the network model pays attention to the effective features of the image segmentation area and eliminates background noise. The results show that the mean cross-union ratio, Dice coefficient, sensitivity, specificity, accuracy and other indicators of the proposed algorithm are 91.39%, 92.81%, 89.14%, 99.95% and 95.78%, respectively.

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  • 收稿日期:2023-04-28
  • 最后修改日期:2023-07-06
  • 录用日期:2023-07-23
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